Its a good thing Borderlands has so many guns because youll need to be extra-prepared for these tough boss fights. For this list, were looking at the most insane and psychotic bosses weve ever encountered across the Borderlands franchise. Our list includes the Empyrean Sentinel from Borderlands: The Pre-Sequel (2014), Billy the Anointed from Borderlands 3 (2019), the Destroyer from Borderlands (2009), and more! Did any of these bosses give you a hard time? Share your frustration with us in the comments below.

Watch more great boss fight videos here:
The 10 BEST Bosses In Lego Games: https://youtu.be/M_yoJepF-Yg
The 10 HARDEST Elden Ring Bosses: https://youtu.be/CvJqGcqamNo
The 10 WORST Batman Arkham Boss Fights: https://youtu.be/uQGoniRIGZ4

Big thanks to all the channels featured in our video!
Shirrako: https://www.youtube.com/channel/UC7eAfUjR9gdIjoaoQaS0W-A
Noctober: https://www.youtube.com/channel/UCUDTue0vG26TWpBcLhsjUDg
Generic Gaming: https://www.youtube.com/channel/UCWSfEWhyuPPOAsFsVYIeYgQ
Pallas7: https://www.youtube.com/channel/UC9MYgDcis-EGpPZyF6R-Vjw
ViciousKiwi: https://www.youtube.com/channel/UCQIbAv4jCIr1mFrZwtM8fhg
100% Guides: https://www.youtube.com/channel/UCRvx1nQZ-YXvxc6IOB8mKPg
JELLIS Gamer: https://www.youtube.com/channel/UC6Eq24RUh-ry84HDUBo7IoQ
Bob Hall: https://www.youtube.com/channel/UCQgXmLWlIRVNvLvfVv9C-DQ
reddi41: https://www.youtube.com/channel/UCef-dfsUC_XMAlJRbLSDGIg

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