Over its long run on TV, The Simpsons has focused on some pretty serious things. For this list, well be looking at the best examples of The Simpsons addressing serious issues on this otherwise comedic show. Our countdown includes hot topics like political corruption, same-sex marriage, depression, overmedication, and more! Whats your favorite serious Simpsons episode? Let us know in the comments.

Watch more great videos on The Simpsons here:
Top 10 Creepiest Simpsons Moments Ever: https://youtu.be/sfaWlkjHsTc
Top 10 Times The Simpsons Were Censored: https://youtu.be/F9RBdaUshRY
Top 10 Times The Simpsons Caused Outrage: https://youtu.be/-xtIa9n4HWQ

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