The best laid plans of mice and men often go awry. For this list, well be looking at fictional characters from various media who tried to create a cure of some kind, only for it to go wildly wrong and turn them into the bad guy. Our countdown includes Harry Osborn aka Green Goblin, Victor Fries aka Mr. Freeze, Ichirö Yashida aka Silver Samurai, and more! Are there any instances we missed? Cure our oversight in the comments!

Watch more great villain videos here:
Top 20 Actors Who Always Play Villains: https://youtu.be/er8HtRUdJ90
Top 20 Best Movie Villains of the Century So Far: https://youtu.be/4EIbHLP_zNU
Top 10 Pixar Villains with the Saddest Backstories: https://youtu.be/BhDE4Y_VSeA

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